✉news ScienceBiology first seen 9 h ago, last 53 min ago, peak #1
Methylated eEF1A found to shape cancer protein production
Original: Methylated eEF1A selectively decodes mRNA to shape cancer proteomes
Researchers report that methylated eEF1A, a core protein in cellular translation, selectively decodes mRNA in ways that reshape the proteome of cancer cells. The finding, published in Nature, suggests a chemical modification on this translation factor can influence which proteins tumour cells produce, pointing to a possible mechanism cancer cells use to adapt and a potential target for future therapies.
Why now: It is a newly published Nature study revealing a mechanism by which a translation-factor modification can alter protein output in cancer.
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