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Methylated eEF1A found to shape cancer proteomes

Original: Methylated eEF1A selectively decodes mRNA to shape cancer proteomes

A study published in Nature reports that methylated eEF1A, a translation elongation factor, selectively decodes specific mRNA sequences, thereby influencing which proteins are produced in cancer cells. The finding suggests a new layer of translational control that shapes cancer proteomes, potentially opening avenues for therapeutic targets in tumour biology.

Why now: A new Nature study reveals a previously unknown mechanism by which translation machinery regulates protein production in cancer.

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