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- 1ADA2 protein found to control mitochondrial fitness and interferon activation▼ADA2 controls autophagy-dependent mitochondrial fitness to restrain type I interferon activation
Researchers report in Nature that the ADA2 protein regulates autophagy-dependent mitochondrial fitness, restraining activation of type I interferon signaling. The finding links mitochondrial quality control to immune regulation and may offer insight into interferon-driven inflammatory disease mechanisms.
- 2New review explains why autophagy can help or harm●Autophagy: why a cell’s recycling system can help or harm Autophagy helps cells recycle damaged parts. A new review expl
A new scientific review examines autophagy, the process by which cells recycle their own damaged components. The review argues that manipulating autophagy could benefit patients in some diseases while worsening outcomes in others, highlighting why context matters when developing therapies that target this cellular recycling system.