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ADA2 protein found to control mitochondrial fitness and interferon activation

Original: ADA2 controls autophagy-dependent mitochondrial fitness to restrain type I interferon activation

Researchers report in Nature that the ADA2 protein regulates autophagy-dependent mitochondrial fitness, restraining activation of type I interferon signaling. The finding links mitochondrial quality control to immune regulation and may offer insight into interferon-driven inflammatory disease mechanisms.

Why now: A new Nature study reveals a previously unknown mechanism linking mitochondria and innate immune signaling

ADA2Naturetype I interferon

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