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NFL Week 4 picks: 49ers-Broncos and London games draw predictions

Original: NFL Week 4 odds, predictions, expert picks: Who wins 49ers-Broncos showdown? Colts or Commanders in London?

NFL Week 4 is underway with oddsmakers and analysts weighing in on the weekend's key matchups. Attention is focused on the showdown between the San Francisco 49ers and Denver Broncos, plus the Indianapolis Colts facing the Washington Commanders in the NFL's international series game in London. Expert picks and betting odds are being published as fans debate which contenders will cover.

Why now: Week 4 of the NFL season is happening now, with marquee matchups driving betting and prediction interest.

San Francisco 49ersDenver BroncosIndianapolis ColtsWashington CommandersNFL

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• NFL Week 4 odds, predictions, expert picks: Who wins 49ers-Broncos showdown? Colts or Commanders in London? · CBS Sports

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