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Rethinking reproducibility in advanced 3D cell models

Drug Discovery News examines the reproducibility challenges facing advanced 3D cell models, such as organoids and spheroids, which are increasingly used in drug discovery and disease research. The piece explores why these complex systems can be difficult to replicate consistently across labs and what the field can do to improve standardization, protocol design, and experimental reliability as adoption of 3D models grows.

Why now: 3D cell models are rapidly being adopted in drug development, making questions about how reliable and reproducible they are newly urgent for researchers.

Drug Discovery News3D cell modelsorganoidsdrug discovery

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