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Study maps tumor genes across ages to explain early-onset colorectal cancer

Original: A tumor transcriptomic atlas across eight decades of life reveals distinct features of early-onset colorectal cancer

Researchers publishing in Nature have built a transcriptomic atlas of tumors spanning eight decades of life, revealing that early-onset colorectal cancer has distinct molecular features compared with cases diagnosed later. The findings offer new biological clues behind rising diagnoses in younger adults and may guide age-specific screening and treatment approaches.

Why now: Early-onset colorectal cancer is rising globally, and new molecular evidence explaining how it differs is drawing attention.

Naturecolorectal cancerearly-onset colorectal cancer

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Evidence

• A tumor transcriptomic atlas across eight decades of life reveals distinct features of early-onset colorectal cancer · Nature

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