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Genetic combinations linked to membranous nephropathy identified

Original: Canonical correlation analysis identifies single nucleotide polymorphism combinations and gene expression associated with membranous nephropathy

Researchers have applied canonical correlation analysis to identify combinations of single nucleotide polymorphisms and gene expression patterns associated with membranous nephropathy, a kidney disease that can cause protein loss and renal failure. By linking genetic variants with gene activity, the study offers a multivariate view of the disease's molecular basis and could help guide future biomarker research.

Why now: A new peer-reviewed study linking genetic variants to a kidney disease is of interest to genomics and nephrology researchers.

membranous nephropathycanonical correlation analysisNature

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