✉news ScienceBiology first seen 2 d ago, last 2 d ago, peak #37
UK Biobank builds 490,319-genome reference panel for global imputation
Original: A haplotype reference panel constructed from 490,319 UK Biobank genomes improves genotype imputation for global populations
Researchers have constructed a haplotype reference panel from 490,319 whole genomes in the UK Biobank, reporting that it improves genotype imputation accuracy for populations worldwide, not just those of European ancestry. Published in Nature, the work gives genetic studies a broader reference resource, potentially reducing biases in disease-gene discovery for underrepresented groups.
Why now: A major new genetics resource promises fairer, more accurate genomic analysis across diverse global populations.
Evidence
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