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Yhn HealthMental Health first seen 7 d ago, last 2 h ago, peak #1

One-Shot CRISPR Therapies Targeting PCSK9 Gain Attention

Original: In-Vivo CRISPR/Base-Editing "One-Shot" Therapies Targeting PCSK9

A newly published review in Current Atherosclerosis Reports examines in-vivo CRISPR and base-editing therapies that target PCSK9, a gene that regulates cholesterol levels. The approach would require only a single treatment to permanently lower LDL cholesterol, potentially replacing daily statins for some patients. Early trials of similar one-time gene-editing cholesterol therapies have generated excitement about the future of cardiovascular prevention.

Why now: Fresh publication of a scientific review on a promising single-dose gene-editing treatment for high cholesterol

PCSK9CRISPRCurrent Atherosclerosis ReportsSpringer

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