✉news ScienceBiology first seen 1 d ago, last 10 h ago, peak #9
Keratin 9 found to regulate mechanosensitive YAP1 signalling in palm skin
Original: Keratin 9 regulates mechanosensitive YAP1 signalling in palmoplantar epidermis
Researchers report in Nature that keratin 9, a protein specific to the thick skin of palms and soles, regulates YAP1, a mechanosensitive signalling pathway that responds to physical forces. The finding clarifies how palmoplantar skin maintains its structure and may inform research on skin thickening disorders and mechanobiology more broadly.
Why now: A new Nature study reveals a previously unknown mechanical signalling role for keratin 9, advancing understanding of specialised skin biology.
Naturekeratin 9YAP1palmoplantar epidermis
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