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Ancient Hox9-10 genes linked to origins of vertebrate limbs

Original: Ancient Hox9–10 genes reveal the hidden origins of vertebrate hind fins and limbs

New research suggests the ancient Hox9-10 gene family played a key role in the evolution of hind fins and limbs in vertebrates. The findings indicate these developmental genes helped pattern the posterior body region, shedding light on how paired appendages first arose in early fish and were later adapted into the limbs of land vertebrates, including humans.

Why now: Fresh research on the genetic origins of limbs is drawing attention from scientists and science readers interested in evolutionary biology.

Hox9-10 genesvertebrates

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