Mmastodon HealthHealth first seen 18 h ago, last 1 h ago, peak #1

Study links gene regulation to why large dogs die younger

Original: 🐕 NEW: Biologists analyzed # DNA methylation across 864 # dogs in the Dog Aging Project, comparing how genes are regulat

Biologists with the Dog Aging Project analyzed DNA methylation in 864 dogs, examining how genes are regulated rather than their underlying sequence. The findings shed light on why large dog breeds tend to have shorter lifespans than smaller ones, a long-standing puzzle in canine biology. Science and pet communities are sharing the results, highlighting what epigenetics can reveal about aging in animals.

Why now: The new study offers a fresh epigenetic explanation for a widely pondered question: why bigger dogs live shorter lives.

Dog Aging Projectdogs

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Evidence

• 🐕 NEW: Biologists analyzed # DNA methylation across 864 # dogs in the Dog Aging Project, comparing how genes are regulated rather than what they say. 👉 https://www. popsci.com/science/why-large-d ogs-die-younger/ # aging # genetics # science # longevity # pets # biology #… · tksst@fediscience.org · 11

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