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Trapping cancer-driving DNA rings in cellular prisons
Original: Small DNA rings can drive tumor growth. But when trapped in cellular “prisons” called micronuclei, they lose their effec
Researchers at Charité Berlin and the Max Delbrück Center report that small DNA rings, which can drive tumor growth, lose their cancer-promoting effect when trapped inside micronuclei, compartments in the cell described as prisons. The team is now searching for compounds that could push more of these DNA rings into micronuclei, potentially opening a new route for cancer therapies.
Why now: A new study from Berlin researchers suggests a possible therapeutic strategy against tumor growth.
Charité BerlinMax Delbrück Center for Molecular Medicinemicronuclei
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Evidence
- Small DNA rings can drive tumor growth. But when trapped in cellular “prisons” called micronuclei, they lose their effect, as researchers at # CharitéBerlin and @ MDC_Berlin show in a new study. The team is now looking for compounds that can steer more of these DNA rings into… · ChariteBerlin@wisskomm.social · 7
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