✉news ScienceBiology first seen 1 d ago, last 21 h ago, peak #17
Simulations Show Enzyme Shape Changes Drive Molecular Recognition
Original: Enzyme’s Changing Shape Steers Molecular Recognition, Simulations Show
New simulation research indicates that an enzyme's shifting shape plays a key role in how it recognises and binds to molecules. Rather than acting as a rigid lock, the enzyme appears to steer molecular recognition through conformational changes, a finding that could inform drug design and deepen understanding of biochemical reactions. Further details of the study, including which enzyme was examined and where the work was published, have not been specified.
Why now: Findings that challenge the classic rigid lock-and-key model of enzyme function are of broad interest to biochemists and drug developers.
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Evidence
- Enzyme’s Changing Shape Steers Molecular Recognition, Simulations Show · Bioengineer.org
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