✉news ScienceBiology first seen 13 h ago, last 1 h ago, peak #9
RBBP5 Found to Control the Cell's 12-Hour Proteostasis Clock
Original: RBBP5 Emerges as a Master Epigenetic Switch Controlling the Cell’s 12-Hour Proteostasis Clock
Researchers report that RBBP5, a core component of histone-modifying complexes, acts as a master epigenetic switch governing the cell's 12-hour ultradian rhythm of protein quality control. The finding suggests this internal proteostasis clock influences how cells manage protein folding and clearance, with possible implications for aging and protein-misfolding diseases. The work is drawing attention among molecular biology and chronobiology observers.
Why now: New research identifies RBBP5 as a key regulator of a recently characterized 12-hour cellular clock, a notable advance in understanding internal rhythms.
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Evidence
- RBBP5 Emerges as a Master Epigenetic Switch Controlling the Cell’s 12-Hour Proteostasis Clock · Bioengineer.org
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