✉news ScienceBiology first seen 23 h ago, last 13 h ago, peak #7
Scientists use CRISPR to manipulate rRNA levels
Original: Manipulating rRNA levels with CRISPR
A Nature paper describes a CRISPR-based approach for manipulating ribosomal RNA levels in cells. Ribosomal RNA makes up the bulk of a cell's RNA, but it has been difficult to study because the genes encoding it exist in many repeated copies. The new method gives researchers a way to tune rRNA abundance directly, which could shed light on how ribosome production drives cell growth, ageing and disease.
Why now: The publication of a new Nature study on a technically difficult CRISPR application is drawing attention from the biology community.
Rank over time, top of the chart is #1. 7 snapshots from 23 h ago to 13 h ago.
Evidence
- Manipulating rRNA levels with CRISPR · Nature
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