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✉news ScienceBiology first seen 10 h ago, last 36 min ago, peak #3

Mendelian randomization takes center stage in the big data era

Original: Mapping causal biology: Mendelian randomization in the era of big data

A new science release examines Mendelian randomization, a statistical method that uses genetic variation to establish causal links between risk factors and disease. Researchers argue that with massive biobank and genome datasets now available, the approach is becoming a central tool for mapping causal biology, while debates continue over its assumptions, limitations and potential for misuse.

Why now: Growing availability of large genetic datasets is pushing the research community to reassess how causal claims in biology are established.

Mendelian randomizationgenomicsbiobanks

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