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Trends
- 1Single CRISPR Treatment Halves Bad Cholesterol for a Year▼One CRISPR treatment cut “bad” cholesterol in half for a full year
A one-time CRISPR gene-editing treatment reportedly cut LDL, or "bad," cholesterol roughly in half, with effects lasting a full year. The finding suggests gene editing could one day offer a durable alternative to daily statins for people at risk of heart disease. Coverage is drawing attention to the potential of permanent, single-dose therapies for one of the world's leading causes of death, though longer and larger trials will be needed before wide use.
- 2
A new essay argues that the scientific consensus linking dietary cholesterol and blood cholesterol to heart disease is flawed, and that statin medications are widely overprescribed with side effects that outweigh benefits for most patients. Readers are debating the claims, with some questioning mainstream cardiology guidance and others defending the evidence base behind statins, one of the most prescribed drug classes in the world.