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esketamine

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    Esketamine shifts microglia from inflammatory state in cell study▼Esketamine steers microglia away from inflammatory state via NMDAR2A in cell study✉newsScienceBiology5 d ago

    A laboratory cell study reports that esketamine, the antidepressant related to ketamine, appears to steer microglia — the brain's immune cells — away from an inflammatory state, acting through the NMDAR2A receptor. The finding, covered by science news outlet Bioengineer.org, may offer a clue to how the drug works beyond its known effects on depression symptoms.