Insomnia

A clinical trial testing a drug candidate for prion disease has started enrolling participants, according to the Broad Institute. Prion diseases, such as fatal familial insomnia and Creutzfeldt-Jakob disease, are rare, rapidly fatal neurodegenerative conditions with no approved treatment, so the start of a trial is a significant step for affected families and researchers. Details on the drug's mechanism, trial size, and timeline were not provided.