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human genome
Trends
- 1New guidance for selecting adenine base editors in human genome editing●Rational selection of SpCas9 and variant-derived adenine base editors for human genome editing
A study published in Nature presents a rational framework for choosing between SpCas9 and variant-derived adenine base editors when editing the human genome. The work helps researchers match editor choice to specific target sites, improving precision and efficiency of base-editing experiments and supporting safer therapeutic applications.