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    mRNA vaccine for melanoma draws fresh attention▼News of Note: mRNA vaccine for melanoma✉newsHealthMedicine19 min ago

    A melanoma vaccine built on mRNA technology is being highlighted in medical news. The approach, similar to the technology used in some Covid-19 vaccines, is being studied as a way to train the immune system to recognize and attack melanoma cancer cells. If proven effective in trials, it could add a new personalized immunotherapy option for patients with advanced skin cancer.

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    New synthetic lethal drug targets microsatellite instability cancers●A synthetic lethal drug for microsatellite instability cancers✉newsHealthMedicine19 min ago

    Researchers have reported the development of a synthetic lethal drug aimed at cancers with microsatellite instability, a genetic feature found in colorectal and other tumor types. Synthetic lethality exploits mutations unique to cancer cells, sparing healthy tissue. The work was published in Nature, and scientists say such drugs could expand treatment options for patients whose tumors resist existing immunotherapies.

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    p53 shown to prevent chromothripsis by balancing transcription and replication●p53 keeps a transcription–replication balance that prevents chromothripsis✉newsScienceBiology28 min ago

    Research published in Nature reports that the p53 tumour suppressor protein maintains a balance between transcription and DNA replication, and that this balance prevents chromothripsis, a catastrophic form of chromosome shattering linked to cancer. The finding adds to understanding of how p53 suppresses tumours beyond its established roles in cell-cycle control and apoptosis, and highlights genome instability mechanisms relevant to cancer research.

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    13-Year-Old Reported Cured of Deadly Brain Cancer DIPG●A 13-Year-Old Has Been Cured of DIPG, the Deadliest Childhood Brain CancerYhnWorld131 h ago

    A 13-year-old has reportedly become the first patient cured of DIPG, an aggressive and almost universally fatal childhood brain cancer. The announcement, described as a world first, is drawing attention because DIPG has resisted decades of treatment efforts, with most children diagnosed surviving less than a year. If confirmed, it could mark a turning point in pediatric cancer research.

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    Aeon essay argues for dropping the 'C-word' for cancer●Don't use the 'C-word' https://aeon.co/essays/we-need-a-better-way-to-describe-what-is-often-called-cancer # Science # HMmastodonScience320 min ago

    An essay in Aeon argues that the word 'cancer' should be used far more cautiously, since the term lumps together conditions of wildly different danger and leads to overdiagnosis and overtreatment. The author calls for a better vocabulary to describe what is often called cancer, arguing that language shapes how patients understand risk and choose treatment.

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    News coverage is highlighting lung cancer cases in people who have never smoked, a group historically overlooked in screening and public awareness. Reports note that never-smokers can develop the disease, often at later diagnosis, and discussion is focusing on possible causes such as air pollution, genetic factors, and radon exposure, as well as what this means for screening guidelines and research funding.

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    Cancer vaccines emerge as promising new frontier in medicine●She was ready to die. Now she’s in remission — cancer vaccines could be the next big thing in medicine✉newsHealthMedicine19 min ago

    A terminal cancer patient who had accepted she was dying is now in remission after receiving an experimental cancer vaccine. Doctors say the case highlights the growing potential of personalized cancer vaccines, which train the immune system to attack tumors. The story is fueling optimism that such vaccines could become a major new tool in cancer treatment.

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    TTUHSC says Edison System destroys cancers without surgery●TTUHSC 'Edison System' destroys certain cancers without surgery✉newsTechnology40 min ago

    Texas Tech University Health Sciences Center has announced the Edison System, a technology it says can destroy certain cancers without the need for surgery. The claim, reported by the Amarillo Globe-News, suggests a non-invasive alternative for treating selected tumors. Details on how the system works, which cancer types it targets, and whether clinical testing has begun have not been made available, so the announcement should be treated as an early claim pending independent confirmation.

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    Aptadir raises €40M to advance demethylating medicines●Aptadir has €40M warchest to advance demethylating medicines✉newsBusinessStartups46 min ago

    Spanish biotech Aptadir has secured a €40 million funding package to advance its demethylating medicines, a class of therapies targeting epigenetic changes in cancer cells. The company says the new capital will support development of its pipeline of epigenetic drug candidates as it moves toward clinical progress.

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    Study Finds Proliferative Pause Could Help Prevent Brain Metastasis●Proliferative Pause Reveals Window to Prevent Brain Metastasis✉newsHealthMedicine1 h ago

    Researchers report that a 'proliferative pause' — a dormant phase cancer cells enter before spreading — may offer a critical window to intervene and stop brain metastasis before it takes hold. The findings, covered by Inside Precision Medicine, suggest targeting cells during this quiet period could prevent secondary brain tumours, a major cause of death in patients with advanced cancers such as breast cancer and melanoma.