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- 113-Year-Old Cured of DIPG, the Deadliest Childhood Brain CancerβA 13-Year-Old Has Been Cured of DIPG, the Deadliest Childhood Brain Cancer
A 13-year-old has reportedly become the first patient cured of DIPG, an aggressive and almost universally fatal childhood brain cancer. The claim, described as a world first, is drawing wide attention because DIPG has resisted decades of treatment efforts, with most children surviving less than a year after diagnosis. Commenters are discussing the significance for pediatric cancer research and what the treatment could mean for future patients.
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Health outlets are highlighting an mRNA vaccine being developed for melanoma, the deadliest form of skin cancer. The approach uses the same mRNA technology proven in COVID-19 vaccines, training the immune system to recognize and attack tumor cells. WVU Medicine shared the update, and the item is drawing attention as trials of personalized cancer vaccines continue to advance globally.
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A new trial reports that stereotactic radiosurgery improves survival for patients with small cell lung cancer that has spread to the brain. The findings challenge the routine use of whole-brain radiation therapy for these patients and are drawing attention among oncologists, with searches about cancer trending in Australia and France.
- 4AstraZeneca invests $2bn in cancer drug partnership with Summit Therapeuticsβπ Astrazeneca invests $2bn in cancer drug tie-up Astrazeneca has invested $2bn in US pharmaceutical firm Summit Therapeu
AstraZeneca has invested $2bn in US biotech firm Summit Therapeutics as part of a major cancer research collaboration. The FTSE 100 drugmaker agreed to buy 109,000 shares in the Nasdaq-listed company at $18.36 per share, funding a tie-up aimed at developing new cancer treatments.
- 5CAR T cell therapy shows two years free of lupus flaresβTwo years later, CAR T cell therapy shows promise for life without lupus flares
Researchers at UMass Chan Medical School report that lupus patients treated with CAR T cell therapy have remained free of disease flares two years after receiving the one-time cell-based treatment. The therapy, originally developed for blood cancers, reprograms a patient's own immune cells, and the latest follow-up data suggest it may offer lasting remission in autoimmune disease.
- 6p53 found to prevent chromothripsis by balancing transcription and replicationβΌp53 keeps a transcriptionβreplication balance that prevents chromothripsis
New research reported in Nature shows that the p53 protein, best known as a tumour suppressor, maintains a balance between transcription and DNA replication in cells. When this balance is disrupted, chromosomes can shatter in a catastrophic event known as chromothripsis, a recognised driver of cancer. The findings clarify how p53 guards genome integrity beyond its established roles in halting damaged cells.
- 7Study Finds Proliferative Pause Could Help Prevent Brain MetastasisβΌProliferative Pause Reveals Window to Prevent Brain Metastasis
Researchers report that a 'proliferative pause' β a dormant phase cancer cells enter before spreading β may offer a critical window to intervene and stop brain metastasis before it takes hold. The findings, covered by Inside Precision Medicine, suggest targeting cells during this quiet period could prevent secondary brain tumours, a major cause of death in patients with advanced cancers such as breast cancer and melanoma.
- 8Researchers link cell crowding to optimal treatment timingβTreatment resistance is one of the key challenges in cancer and antibiotic therapy. Researchers led by Dr. Jona Kayser a
Researchers led by Dr. Jona Kayser at MPZPM report that physical processes in dense cell populations strongly influence the best timing of treatment cycles, with implications for both cancer therapy and antibiotics. Treatment resistance remains one of the central challenges in medicine, and the findings suggest that timing could be adjusted based on how tightly cells pack together rather than on biology alone. The work points to new ways of scheduling therapies to delay or avoid resistance.
- 9Reproducibility crisis in biomedical research draws renewed scrutinyβΌReproducibility in biomedical research
Biomedical researchers are once again debating how much of the published scientific literature can be reliably reproduced. Concerns that many experimental findings in fields like cancer biology and pharmacology fail when independently repeated have prompted calls for better study design, data sharing and stricter peer review. The discussion continues to shape how journals, funders and laboratories address the reliability of research that ultimately informs medical practice.
- 10Infections Cause 1 in 8 Cancer Cases Worldwide, Study FindsβΌ1 in 8 cancer cases worldwide are caused by infections, study finds
A new study has found that infections cause roughly one in eight cancer cases worldwide. The finding points to the significant role viruses and bacteria play in triggering cancers, suggesting prevention through vaccination and treatment of infections could substantially reduce the global cancer burden.
- 11UConn Health Launches CAR-T Cell Therapy ProgramβUConn Health Launches Cutting-Edge CAR-T Cell Therapy Program
UConn Health has announced the launch of a new CAR-T cell therapy program, a form of immunotherapy that engineers a patient's own immune cells to fight cancer. The initiative brings an advanced, personalised cancer treatment to the Connecticut institution, expanding access for patients in the region who previously had to travel elsewhere for such therapy.
- 12Study reports vitamin C and DMSO shrink skin cancer lesionsβA new study reports promising results using vitamin C + DMSO for skin # cancer , including 56% elimination in 12 weeks a
A new study reports that a combination of vitamin C and DMSO produced promising results against skin cancer, with reported elimination of lesions in 56% of cases within 12 weeks and 94% of patients avoiding surgery. Other research suggests DMSO may enhance delivery of anticancer drugs directly into tumors, and early reports involving ivermectin are also circulating.
- 13New synthetic lethal drug targets microsatellite instability cancersβΌA synthetic lethal drug for microsatellite instability cancers
Researchers have reported the development of a synthetic lethal drug aimed at cancers with microsatellite instability, a genetic feature found in colorectal and other tumor types. Synthetic lethality exploits mutations unique to cancer cells, sparing healthy tissue. The work was published in Nature, and scientists say such drugs could expand treatment options for patients whose tumors resist existing immunotherapies.
- 14Penn Medicine and IBA Launch Proton Therapy Joint VentureβPenn Medicine, IBA Form Joint Venture to Advance Proton Therapy, Radiation Oncology
Penn Medicine and Belgian medical technology company IBA have formed a joint venture aimed at advancing proton therapy and radiation oncology. The partnership will combine Penn Medicine's clinical expertise with IBA's technology to develop and expand proton therapy treatments for cancer patients.
- 15Aeon essay argues for dropping the 'C-word' for cancerβDon't use the 'C-word' https://aeon.co/essays/we-need-a-better-way-to-describe-what-is-often-called-cancer # Science # H
An essay in Aeon argues that the word 'cancer' should be used far more cautiously, since the term lumps together conditions of wildly different danger and leads to overdiagnosis and overtreatment. The author calls for a better vocabulary to describe what is often called cancer, arguing that language shapes how patients understand risk and choose treatment.
- 16Infections cause 1 in 8 cancer cases worldwide, study findsβ1 in 8 cancer cases worldwide are caused by infections, study finds https://www.cbc.ca/lite/story/9.7361622 # HackerNews
A new study finds that roughly one in eight cancer cases worldwide are caused by infections, according to CBC News coverage. The finding highlights the role of viruses and bacteria in cancer development and has prompted discussion about prevention, vaccination, and screening efforts globally.
- 17GMA correspondent Will Reeve reveals testicular cancer diagnosisβ'GMA' correspondent Will Reeve reveals testicular cancer diagnosis
Will Reeve, a correspondent for ABC's Good Morning America and son of the late actor Christopher Reeve, has announced that he has been diagnosed with testicular cancer. He shared the news publicly, drawing an outpouring of support from viewers and colleagues, and adding to his well-known advocacy work around health and disability issues following his father's legacy.
- 18Theranostics offers new approach for advanced prostate cancerβ'Theranostics' combines diagnostics and therapy for advanced prostate cancer treatment
Doctors are highlighting theranostics, an emerging approach to treating advanced prostate cancer that pairs diagnostic imaging with targeted therapy in a single process. The method allows physicians to detect cancer cells and deliver radiation treatment directly to them, potentially improving outcomes for patients whose disease no longer responds to standard therapies.
- 19All-Male Pink Fashion Show Returns for Breast Cancer AwarenessβAll Male Pink Fashion Show returns to support breast cancer awareness
The All-Male Pink Fashion Show is returning, with proceeds and attention directed toward breast cancer awareness. The event puts men on the runway wearing pink to raise funds and public support for the cause. Organizers hope its return will renew community engagement and boost awareness efforts, though further details about the date, location, and beneficiaries have not been reported.
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A new report from Cure Today outlines how artificial intelligence could support doctors across the full cancer care team, from diagnosis and treatment planning to follow-up care. It argues AI tools may help oncologists, radiologists and other specialists work more efficiently and coordinate care, while cautioning that clinical oversight remains essential as adoption grows.
- 21Cancer vaccine puts terminal patient into remissionβΌExclusive | She was ready to die. Now sheβs in remission β cancer vaccines could be the next big thing in medicine
A woman who had been prepared to die has entered remission after receiving an experimental cancer vaccine, in a report highlighting the technology as a possible next major advance in medicine. The case is being presented as evidence that therapeutic vaccines, which train the immune system to attack tumors, could transform cancer treatment.
- 22ABC News anchor Will Reeve reveals testicular cancer diagnosisβABC News' Will Reeve reveals testicular cancer diagnosis, chemotherapy treatment
Will Reeve, an ABC News correspondent and son of the late Superman actor Christopher Reeve, has announced that he has been diagnosed with testicular cancer and is undergoing chemotherapy treatment. The news is being picked up widely by US media outlets, with viewers and colleagues offering support and praising his decision to share the diagnosis publicly.
- 23Haga Bioscience and Imagenomix Partner on AI Cancer PathologyβHaga Bioscience, Imagenomix Partner for AI Spatial Biomarker Analysis in Cancer Pathology
Haga Bioscience and Imagenomix have announced a partnership to develop AI-based spatial biomarker analysis for cancer pathology. The collaboration aims to combine spatial biology techniques with artificial intelligence to improve how biomarkers are measured in tumor tissue, potentially supporting more precise cancer diagnosis and treatment decisions.
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News coverage is highlighting lung cancer cases in people who have never smoked, a group historically overlooked in screening and public awareness. Reports note that never-smokers can develop the disease, often at later diagnosis, and discussion is focusing on possible causes such as air pollution, genetic factors, and radon exposure, as well as what this means for screening guidelines and research funding.
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Flechas de Vida, an archery programme for people affected by breast cancer, has published a book. The initiative, supported by World Archery, uses archery to help breast cancer patients and survivors with physical recovery and confidence. The book documents the programme's experience and is expected to reach a wider audience of practitioners and adaptivesport organisers worldwide.
- 26Cancer vaccines emerge as promising new frontier in medicineβShe was ready to die. Now sheβs in remission β cancer vaccines could be the next big thing in medicine
A terminal cancer patient who had accepted she was dying is now in remission after receiving an experimental cancer vaccine. Doctors say the case highlights the growing potential of personalized cancer vaccines, which train the immune system to attack tumors. The story is fueling optimism that such vaccines could become a major new tool in cancer treatment.
- 27TTUHSC says Edison System destroys cancers without surgeryβTTUHSC 'Edison System' destroys certain cancers without surgery
Texas Tech University Health Sciences Center has announced the Edison System, a technology it says can destroy certain cancers without the need for surgery. The claim, reported by the Amarillo Globe-News, suggests a non-invasive alternative for treating selected tumors. Details on how the system works, which cancer types it targets, and whether clinical testing has begun have not been made available, so the announcement should be treated as an early claim pending independent confirmation.
- 28Aptadir raises β¬40M to advance demethylating medicinesβAptadir has β¬40M warchest to advance demethylating medicines
Spanish biotech Aptadir has secured a β¬40 million funding package to advance its demethylating medicines, a class of therapies targeting epigenetic changes in cancer cells. The company says the new capital will support development of its pipeline of epigenetic drug candidates as it moves toward clinical progress.