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Y chromosome
Trends
- 1Missing Y chromosome pieces found to drive cancer in men▼Study shows how missing pieces of Y chromosome drive cancer in men
A new study shows how loss of parts of the Y chromosome, a common age-related change in men's cells, can promote cancer growth. Researchers report the missing pieces help tumours evade immune defences, offering a possible explanation for why some cancers in men are more aggressive and opening paths to new treatments.
- 2Y chromosome loss found recurrently disrupted in cancers●Recurrent deletions and regulatory disruption of the Y chromosome in cancer
Researchers have documented recurrent deletions and regulatory disruption of the Y chromosome across cancer types, according to a study published in Nature. The work suggests loss or alteration of Y chromosome genetic material may play a functional role in tumour development rather than being incidental, opening questions about how such changes influence cancer biology and potential sex-based differences in disease.