The Truth

Canada is observing the National Day for Truth and Reconciliation, honouring the children who died at residential schools and the survivors and communities affected by the system. People are sharing commemorations, orange shirts and reflections on reconciliation efforts, with renewed debate about how far the country has come and how much work remains.

Eric Topol, a prominent American physician-scientist, argues that aging in humans is driven substantially by the loss of cell identity: as cells age, they drift from their specialised roles, which undermines tissue function and contributes to age-related disease. Writing on his Ground Truths platform, he frames this cellular reprogramming as a central mechanism in the biology of aging, a topic of growing interest in longevity research.